(in building)

1. Real-time raw signal genomic analysis with in-memory computing

Nanopore genomic analysis typically requires two computationally intensive steps: basecalling and read mapping, both demanding frequent and costly data movement on Von Neumann hardware.

This work inroduced a memristor-based hardware-software co-design, that directly analyze the raw signals using in-memory computing hardware, effectively combining separate basecalling and read mapping.

References:

• P. He, et al., Real-time raw signal genomic analysis using fully integrated memristor hardware. Nature Computational Science 5, 940–951 (2025).